LeReve Wellness – Advanced Restorative Solutions for Spine, Joint, and Musculoskeletal Pain
A globally recognized authority in the fields of restorative medicine and interventional pain management, Annu Navani, MD, serves as the Founder and CEO of LeReve Wellness and the Chief Medical Officer at Boomerang Healthcare. With a distinguished career spanning over two decades, including 20 years as Adjunct Clinical Associate Professor at Stanford University School of Medicine, Dr. Navani has established herself as a visionary researcher and innovator. Her practice is dedicated to providing cutting-edge solutions for complex musculoskeletal pain and orthopedic concerns, blending mainstream rehabilitative care with the most advanced therapeutic breakthroughs available in modern medicine. Her journey has been defined by a commitment to clinical excellence and a deep-seated passion for advancing the standard of care for patients seeking non-surgical pain relief.
Dr. Navani’s expertise is backed by an elite academic foundation and an unparalleled list of leadership roles. She is the President-Elect of the American Society of Interventional Pain Physicians (ASIPP) and the Founder and Chair of the World Institute of Regenerative Medicine (WIRM). Triple board-certified in Anesthesiology, Pain Medicine, and Regenerative Medicine, Dr. Navani is a prolific author whose book, “Essentials of Regenerative Medicine,” is a seminal text illustrating the latest interventional biologic techniques for spine and joint injuries. She has been instrumental in authoring national clinical guidelines for the safe and effective use of orthobiologics, ensuring that her patients receive care that is both innovative and rigorously evidence-based.
Driven by a passion for patient wellness and anti-aging innovation, Dr. Navani empowers her patients to achieve their health goals through personalized, forward-thinking care. Whether addressing chronic spinal issues or advancing the field of applied biologics, she remains committed to restoring function and improving quality of life. Her mission is to merge the latest scientific advancements with a compassionate, patient-centered approach, creating customized care plans that help individuals not just manage symptoms, but truly thrive. By integrating her deep knowledge of regenerative medicine with a focus on holistic recovery, she provides a path to healing for those seeking alternatives to traditional surgery.
Genesis® Regenerative Protein Arrays
In her pursuit of the most sophisticated restorative tools, Dr. Navani incorporates the Genesis® Regenerative Protein Array (RPA) into her clinical practice. RPA represents the next generation of healing, moving a “generation beyond” traditional modalities like Platelet-Rich Plasma (PRP) or stem cells. As an acellular product, RPA contains no whole cells or DNA, which significantly reduces the risk of adverse reactions, inflammatory spikes, or contraindications. This unique composition makes it a powerful, highly refined option for patients seeking a safe and potent approach to tissue support and repair.
The efficacy of RPA is rooted in its ability to harness the body’s innate intelligence through paracrine signaling—a process where bioactive molecules communicate directly with the patient’s own cells. Each array contains over 80 different signaling molecules, including cytokines, growth factors, and miRNA. Due to this comprehensive range of regenerative factors, RPA is estimated to be up to 1,000 times more potent than PRP. Rather than introducing foreign cells, RPA delivers a complex biochemical “blueprint” designed to help “reprogram” the local environment of damaged or diseased tissues, activating and orchestrating the body’s natural healing capabilities.
Dr. Navani utilizes RPA within a “body-centric” framework, ensuring the therapy supports the natural biological processes already present within the patient. This Genesis® product is ethically sourced from pristine placentas donated after healthy, scheduled, live C-section births. To ensure the highest levels of purity and safety, RPA is produced in FDA-registered facilities. This advanced modality allows Dr. Navani to offer her patients a sophisticated alternative that aligns with the highest standards of modern regenerative science.






